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What is Euflexxa^®?

What is Euflexxa^®?

How is Euflexxa^® given?

How quickly does Euflexxa^® work?

How long does Euflexxa^® last?

What side effects are seen with Euflexxa^®?

Is Euflexxa^® covered by insurance?

What else should I know about Euflexxa^®?

What is Euflexxa^®?

Treatment with Euflexxa^®

It's a good idea to learn as much as you can about any new treatment or medication your doctor prescribes. The questions and answers below are designed to help you better understand what to expect from treatment with Euflexxa^®.

What is Euflexxa^®?

Euflexxa^® is a highly purified hyaluronan, also called hyaluronic acid (HA) or sodium hyaluronate. HA is a natural substance found in the fluid that surrounds a healthy knee. This fluid is called synovial fluid and it helps cushion, lubricate, and protect the knee. In people with osteoarthritis (OA) of the knee, the synovial fluid becomes thinner and less able to do its job.

Euflexxa^® is similar to the HA found in healthy knees. When Euflexxa^® is injected into the knee, it replenishes the HA in the knee and helps restore the ability of the synovial fluid to cushion, lubricate, and protect the knee. Euflexxa^® is different from pills because it works right at the source of pain and is not distributed throughout your body.

How is Euflexxa^® given?

Euflexxa^® is injected into the space in your knee joint. Treatment consists of 3 injections–1 injection per week for 3 weeks².

How quickly does Euflexxa^® work?

Some people experience pain relief after the first or second injection of Euflexxa^®, but most people experience significant relief after the third (last) injection.

How long does Euflexxa^® last?

Every person is different. The duration of pain relief with Euflexxa^® varies from one person to the next, but in general you can expect to have many months of pain relief.

What side effects are seen with Euflexxa^®?

Euflexxa^® is highly purified HA and is similar to the HA that occurs naturally in your body. In clinical trials, few side effects were reported, and those that did occur tended to be mild and transient (ie, they did not last long). The only side effect reported by more than 5% of the people who received Euflexxa^® was arthralgia (joint pain)–in 8.75% of people.

Is Euflexxa^® covered by insurance?

Euflexxa^® is covered by most insurance providers. The process of obtaining reimbursement varies from plan to plan. Talk with your doctor's office and your insurance provider before you begin treatment to find out if Euflexxa^® is covered and to learn how to get reimbursed.

You can receive a repeat course of Euflexxa^® once every 6 months.

Medicare: For Medicare coverage, Euflexxa^® must be purchased directly by a doctor for a specific person. Medicare will not cover the cost of individual prescriptions written by doctors and filled by people receiving treatment.

What else should I know about Euflexxa^®?

You should avoid strenuous activities, such as jogging or tennis, for 48 hours after your Euflexxa^® injection

Reference:
1. Data on file. Ferring Pharmaceuticals Inc. 2 Kirchner M, Marshall D. A double-blind randomized controlled trial comparing alternate forms of high molecular weight hyaluronan for the treatment of osteoarthritis of the knee. Osteoarthr Cartil. 2006;14:154-162.

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EUFLEXXA (1% sodium hyaluronate) is indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy and simple analgesics (eg, acetaminophen).

Important Safety Information
EUFLEXXA is contraindicated in patients who have a known hypersensitivity to hyaluronate preparations or who have knee joint infections, infections, or skin disease in the area of the injection site.

EUFLEXXA should not be administered through a needle previously used with medical solutions containing benzalkonium chloride. Do not use skin disinfectants for skin preparation that contain quaternary ammonium salts.

Do not inject intravascularly due to potential for systemic adverse events.

The safety and effectiveness of injection in conjunction with other intra-articular injectables, or into joints other than the knee have not been studied. Remove any joint effusion prior to injecting. Transient pain or swelling of the injected joint may occur after intra-articular injection with EUFLEXXA. The safety and effectiveness of repeated treatment cycles weeks with EUFLEXXA have not been established.

In a randomized, double-blind, multicenter clinical trial (N=160 EUFLEXXA), the only adverse event reported with EUFLEXXA at an incidence greater than 5% was arthralgia (8.7%).

Full Prescribing Information.

Important Information for Patients.

The information on this website is provided for educational purposes only. While there may be information on this web site related to certain medical conditions and their treatment, should a medical condition exist, promptly see your own physician or health provider as the information on this website is not intended to take the place of advice from a physician or healthcare professional. Ferring does not offer personalised medical diagnosis or patient-specific treatment advice. The statements made by doctors on this website represent their own individual experience and opinion and is not intended to be medical advice. Indeed, only your doctor or other health care professional, as a learned intermediary, can determine if a product described in this web site is appropriate for you.

PLEASE CONSULT WITH YOUR DOCTOR, OR OTHER QUALIFIED HEALTH CARE PROFESSIONAL BEFORE USING ANY PRODUCT DISCUSSED WITHIN THIS WEB SITE.

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