Your Moments. Your Euflexxa.

Is it time for EUFLEXXA to be your next therapy?

Life is a series of moments, experiences, and activities. If your osteoarthritis knee pain starts getting in the way of the moments you care about, ask your doctor whether EUFLEXXA is a good next choice to add to your treatment plan for knee osteoarthritis (OA) pain relief. If your over-the-counter or prescription pain medications are no longer working well, it may be the right time to take that next step.

EUFLEXXA is a hyaluronic acid (HA) product that is manufactured from a natural source of HA. The nonbird-derived substance is put through a precise, multistep cleansing and filtering process that creates a highly purified, gel-like HA fluid. EUFLEXXA is for injection into the knee to help replace your knee’s own HA.1,2

EUFLEXXA is used to relieve OA knee pain in people who do not get enough relief from simple pain medications.


When EUFLEXXA is injected into the knee, it replenishes the HA you have lost, helping provide pain relief. Clinical studies have shown that EUFLEXXA may help provide pain relief for up to 6 months.1-6

HA contains a natural substance that is found in the human body as well as in animals and bacteria. In the human knee, HA is a thick, slippery fluid that helps cushion, lubricate, and protect the bones and joint tissue. In patients with OA of the knee, the HA gets thinner over time and becomes less able to provide protection.3

EUFLEXXA is used to relieve OA knee pain in people who do not get enough relief from simple pain medications such as acetaminophen, ibuprofen, or naproxen or from exercise and physical therapy.2

References: 1. Data on file. Bio-Technology General (Israel) Ltd. 2. EUFLEXXA [package insert]. Parsippany, NJ: Ferring Pharmaceuticals Inc. 3. Benke M, Shaffer B. Viscosupplementation treatment of arthritis pain. Curr Pain Headache Rep. 2009;13(6):440-446. 4. What is hyaluronic acid and how does it work for arthritis? Health Tuber website. Accessed October 31, 2016. 5. Altman RD, Rosen JE, Bloch DA, Hatoum HT, Korner P. A double-blind, randomized, saline-controlled study of the efficacy and safety of EUFLEXXA for treatment of painful osteoarthritis of the knee, with an open-label safety extension (the FLEXX Trial). Semin Arthritis Rheum. 2009;39(1):1-9. 6. Kirchner M, Marshall D. A double-blind randomized controlled trial comparing alternate forms of high molecular weight hyaluronan for the treatment of osteoarthritis of the knee. Osteoarthritis Cartilage. 2006;14(2):154-162.

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