What is EUFLEXXA?
EUFLEXXA is an ultra-high purity hyaluronan, also called hyaluronic acid (HA) or sodium hyaluronate. HA is the natural substance found in the fluid that surrounds a healthy knee joint and helps cushion, lubricate, and protect the knee as you move throughout the day. EUFLEXXA is similar to the human HA found in healthy knee joints. When EUFLEXXA is injected into the knee joint, it works by replenishing the HA in the knee and restoring the synovial fluid's ability to cushion, lubricate, and protect the knee joint.
How is EUFLEXXA different?
EUFLEXXA is the first bioengineered (fermentation-derived) HA approved in the United States for OA of the knee.
Made through advanced technology, EUFLEXXA has unprecedented purity. Unlike all other HA products currently on the market for OA of the knee,
EUFLEXXA is not made from processed chicken or rooster combs. In fact, EUFLEXXA is FREE of any animal proteins, so the chance of an allergic response
occurring in people sensitive to poultry products (including eggs and feathers) is eliminated. This means if you are allergic to eggs or poultry products, EUFLEXXA
is the option for you. EUFLEXXA is also different because it requires only 3 injections—1 injection a week for 3 weeks—instead of 5 injections necessary
with some other HA products.
Please see EUFLEXXA Product Information for more details.
Is EUFLEXXA right for me?
If you have been diagnosed with osteoarthritis (OA) of the knee, EUFLEXXA may be right for you if you can’t get satisfactory pain relief or improvement in activity levels…
- With over-the-counter pain medications, such as acetaminophen (Tylenol®)
- With physical therapy, exercise, or weight loss
- With prescription pain medications
Or, if you can’t tolerate…
- Aspirin
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- COX-2 inhibitors
- Other pain medications
- The side effects of prescription pain medications (such as COX-2 inhibitors)
You should not receive treatment with EUFLEXXA if you have:
- A known allergy to hyaluronate preparations
- Knee joint infections, infections or skin disease in the area of the injection site
Be sure to take the
EUFLEXXA Self-Assessment Quiz to help you determine whether you would be a candidate for EUFLEXXA therapy. You can then print the results for further consultation with your doctor.
Tylenol is a registered trademark of McNeil Consumer and Specialty Pharmaceuticals.
How is EUFLEXXA given?
EUFLEXXA is injected into the knee joint space. Treatment consists of 3 injections—1 injection a week for 3 weeks.
How soon can I expect pain relief from EUFLEXXA? How long does it last?
While some people experience pain relief after the first injection of EUFLEXXA, most patients experience significant relief after the third (last) weekly injection. You can expect months of pain relief from EUFLEXXA, although the duration of relief will vary from person to person.
What are some possible side effects of EUFLEXXA therapy?
EUFLEXXA is an ultra-high purity HA and is similar to the HA that already occurs naturally in your body. In clinical trials, few side effects were reported, and those that did occur tended to be mild and transient (they didn't last long). Additionally, 81% of patients reported feeling “satisfied” or “very satisfied” with EUFLEXXA. In a multicenter clinical study, the only side effect reported in more than 5% of people who used EUFLEXXA was arthralgia (joint pain) (8.75%).
What else should I know about EUFLEXXA therapy?
- Temporary knee pain and swelling in the knee may occur after injection with EUFLEXXA
- It is recommended that people avoid any strenuous activities, such as jogging or tennis, within 48 hours following EUFLEXXA injection
- While EUFLEXXA is safe and effective therapy, the safety and effectiveness of EUFLEXXA have not been established when…
- Given with other injectable pain medicines
- Injected into joints other than the knee
- Given in repeated treatment cycles
- If you have latex allergies, please consult your physician prior to beginning EUFLEXXA therapy.
- Euflexxa may be stored at room temperature or in a refrigerator at 2°–25°C (36°–77°F). Protect from light. Do not freeze. If refrigerated, remove from refrigeration at least 20-30 minutes before use.
